Psoriasis is a chronic skin disease characterized by keratinocyte hyperproliferation and dedifferentiation, neoangiogenesis, and inflammation. T cell-mediated immunity, in which cytokines play an essential role. It is characterized by well-defined reddish (erythematous) plaques with large adherent silvery scales. The main defect in psoriasis is an increased proliferation of the skin layers due to excessive division of the cell in the basal layers of the skin. Severe itching may associate with the plaques. Dryness of the skin and silvery scaling are characterized the condition. 1% to 3% of the most population has Psoriasis. Clinically, psoriasis most frequently affects the skin of the elbow, knees, scalp, lumbosacral areas, intergluteal cleft and glans penis. In Ayurveda Psoriasis is caused by vitiation of vata and kapha dosha. There are three kinds of psoriasis called Kitibha, Ekakustha and Charmakhya.
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